Amnesiac Nation

Aging Specifically Impairs amnesiac-Dependent Memory in Drosophila

Age-related memory impairment (AMI) is observed in many species. However, it is uncertain whether AMI results from a specific or a nonspecific decay in memory processing. In Drosophila, memory acquired after a single olfactory conditioning paradigm has three distinct phases: short-term memory (STM), middle-term memory (MTM), and longer-lasting anesthesia-resistant memory (ARM). Here, we demonst...

Mushroom Bodies, Ca2+ Oscillations, and the Memory Gene amnesiac

The memory of odors in Drosophila is mediated by mushroom body neurons. Memory is formed, in part, by a modulation of the physiology of these neurons brought about by neuropeptides that are encoded by the amnesiac gene and released from peptidergic neurons that innervate mushroom body neurons. Slow and spontaneous oscillations of calcium levels are elevated in the mushroom body neurons of amnes...

Nation - building

Nations stay together when citizens share enough values and preferences. Homogeneity amongst people can be built with education, teaching a common language to facilitate communication, but also by brute force such as prohibiting local cultures. Democracies and dictators have different incentives when it comes to choosing how much and by what means to homogenize the population. We study and we c...

The fructose nation.

There is growing miasma in our national correspondence over the increasing heft and metabolic dysfunction of everyday Americans. The origin of this mounting poundage has many parents, not the least of which is our appetite for nutritive (read caloric) sweeteners in processed foods and beverages. The culprit derivatives taking most heat today are various formulations of added fructose. Bray et a...

A nation divided.